Ontology highlight
ABSTRACT:
SUBMITTER: Kwan HY
PROVIDER: S-EPMC4358044 | biostudies-other | 2015 Mar
REPOSITORIES: biostudies-other
Kwan Hiu Yee HY Niu Xuyan X Dai Wenlin W Tong Tiejun T Chao Xiaojuan X Su Tao T Chan Chi Leung CL Lee Kim Chung KC Fu Xiuqiong X Yi Hua H Yu Hua H Li Ting T Tse Anfernee Kai Wing AK Fong Wang Fun WF Pan Si-Yuan SY Lu Aiping A Yu Zhi-Ling ZL
Scientific reports 20150313
Schisandrin B (SchB) is one of the most abundant bioactive dibenzocyclooctadiene derivatives found in the fruit of Schisandra chinensis. Here, we investigated the potential therapeutic effects of SchB on non-alcoholic fatty-liver disease (NAFLD). In lipidomic study, ingenuity pathway analysis highlighted palmitate biosynthesis metabolic pathway in the liver samples of SchB-treated high-fat-diet-fed mice. Further experiments showed that the SchB treatment reduced expression and activity of fatty ...[more]