Pervasive CpG suppression in animal mitochondrial genomes.
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ABSTRACT:
SUBMITTER: Cardon LR
PROVIDER: S-EPMC43669 | biostudies-other | 1994 Apr
REPOSITORIES: biostudies-other
Publications
Pervasive CpG suppression in animal mitochondrial genomes.
Cardon L R LR Burge C C Clayton D A DA Karlin S S
Proceedings of the National Academy of Sciences of the United States of America 19940401 9
All available complete mitochondrial genomes (21 species) are evaluated for dinucleotide over- and under-representation. The CpG dinucleotide is pervasively under-represented in all animal mitochondria, but it is of variable relative abundance in fungal, protist, and plant mitochondrial genomes. Interpretations and hypotheses are considered relative to mitochondrial genome organization, methylation, structural specificities, directed mutation, and evolutionary events. In particular, our results ...[more]
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