Ontology highlight
ABSTRACT:
SUBMITTER: Talluri TR
PROVIDER: S-EPMC4378356 | biostudies-other | 2015 Apr
REPOSITORIES: biostudies-other
Talluri Thirumala R TR Kumar Dharmendra D Glage Silke S Garrels Wiebke W Ivics Zoltan Z Debowski Katharina K Behr Rüdiger R Niemann Heiner H Kues Wilfried A WA
Cellular reprogramming 20150401 2
Induced pluripotent stem cells (iPSCs) are a seminal breakthrough in stem cell research and are promising tools for advanced regenerative therapies in humans and reproductive biotechnology in farm animals. iPSCs are particularly valuable in species in which authentic embryonic stem cell (ESC) lines are yet not available. Here, we describe a nonviral method for the derivation of bovine iPSCs employing Sleeping Beauty (SB) and piggyBac (PB) transposon systems encoding different combinations of rep ...[more]