Ontology highlight
ABSTRACT:
SUBMITTER: Maillard P
PROVIDER: S-EPMC4380772 | biostudies-other | 2015 Apr
REPOSITORIES: biostudies-other
Maillard Pauline P Carmichael Owen T OT Reed Bruce B Mungas Dan D DeCarli Charles C
Neurobiology of aging 20150114 4
Hypertension, hyperlipidemia, and diabetes are increasingly prevalent with advancing age and have been shown to cause white-matter (WM) injury that may contribute to dementia risk. However, cumulative and over time effects of these medical illnesses have not been systematically examined. One hundred twenty-one cognitively normal old participants received comprehensive clinical evaluations and brain diffusion tensor imaging on 2 occasions. Clinical history and medical treatment of diabetes, hyper ...[more]