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Mathematical and computational modeling in biology at multiple scales.

ABSTRACT: A variety of topics are reviewed in the area of mathematical and computational modeling in biology, covering the range of scales from populations of organisms to electrons in atoms. The use of maximum entropy as an inference tool in the fields of biology and drug discovery is discussed. Mathematical and computational methods and models in the areas of epidemiology, cell physiology and cancer are surveyed. The technique of molecular dynamics is covered, with special attention to force fields for protein simulations and methods for the calculation of solvation free energies. The utility of quantum mechanical methods in biophysical and biochemical modeling is explored. The field of computational enzymology is examined.

SUBMITTER: Tuszynski JA

PROVIDER: S-EPMC4396153 | biostudies-other | 2014 Dec

REPOSITORIES: biostudies-other

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Mathematical and computational modeling in biology at multiple scales.

Tuszynski Jack A JA Winter Philip P White Diana D Tseng Chih-Yuan CY Sahu Kamlesh K KK Gentile Francesco F Spasevska Ivana I Omar Sara Ibrahim SI Nayebi Niloofar N Churchill Cassandra Dm CD Klobukowski Mariusz M El-Magd Rabab M Abou RM

Theoretical biology & medical modelling 20141227

A variety of topics are reviewed in the area of mathematical and computational modeling in biology, covering the range of scales from populations of organisms to electrons in atoms. The use of maximum entropy as an inference tool in the fields of biology and drug discovery is discussed. Mathematical and computational methods and models in the areas of epidemiology, cell physiology and cancer are surveyed. The technique of molecular dynamics is covered, with special attention to force fields for ...[more]

PMID: 25542608

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