The correlations between IL-17 vs. Th17 cells and cancer patient survival: a systematic review.
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ABSTRACT:
SUBMITTER: Punt S
PROVIDER: S-EPMC4404813 | biostudies-other | 2015 Feb
REPOSITORIES: biostudies-other
Publications
The correlations between IL-17 vs. Th17 cells and cancer patient survival: a systematic review.
Punt Simone S Langenhoff Jessica M JM Putter H H Fleuren Gert Jan GJ Gorter Arko A Jordanova Ekaterina S ES
Oncoimmunology 20150201 2
Both IL-17 and Th17 cells have been ascribed tumor promoting as well as tumor suppressing functions. We reviewed the literature on correlations between IL-17 versus Th17 cells and survival in human cancer, following the PRISMA guidelines. Serum, formalin-fixed, paraffin-embedded (FFPE) tissue and peripheral blood samples were most frequently studied. High IL-17 quantities were correlated with poor prognosis, whereas high Th17 cell frequencies were correlated with improved prognosis. Since Th17 c ...[more]
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