Ontology highlight
ABSTRACT:
SUBMITTER: Zheng G
PROVIDER: S-EPMC4421815 | biostudies-other | 2015
REPOSITORIES: biostudies-other
Nature communications 20150422
Cascade reactions initiated by radical addition to alkynes are synthetically very attractive because they enable access to highly complex molecular skeletons in only few synthetic steps under usually mild conditions. Here we report a general radical cascade reaction of alkynes, N-fluoroarylsulfonimides and alcohols, enabling the efficient synthesis of important α-amino-α-aryl ketones from readily available starting materials via a single operation. During this process, the highly regioselective ...[more]