Ontology highlight
ABSTRACT:
SUBMITTER: Ananworanich J
PROVIDER: S-EPMC4428158 | biostudies-other | 2015 May
REPOSITORIES: biostudies-other
Ananworanich Jintanat J McSteen Brian B Robb Merlin L ML
Current opinion in HIV and AIDS 20150501 3
<h4>Purpose of review</h4>Infection of long-lived CD4 T cells is a major obstacle to HIV remission, and antiretroviral therapy (ART) instituted during acute HIV infection restricts HIV reservoir establishment. Broadly neutralizing antibodies (bNAbs) may be employed in conjunction with early ART as strategies toward HIV remission.<h4>Recent findings</h4>Proof-of-concept studies in vitro and in animal models demonstrated bNAbs' ability to block viral entry into cells, suppress viremia and reduce c ...[more]