Ontology highlight
ABSTRACT:
SUBMITTER: Sample V
PROVIDER: S-EPMC4436836 | biostudies-other | 2015 May
REPOSITORIES: biostudies-other
Sample Vedangi V Ramamurthy Santosh S Gorshkov Kirill K Ronnett Gabriele V GV Zhang Jin J
Molecular biology of the cell 20150318 10
5'-Adenosine monophosphate-activated protein kinase (AMPK) is a master metabolic regulator that has been shown to inhibit the establishment of neuronal polarity/axogenesis under energy stress conditions, whereas brain-specific kinase (BRSK) promotes the establishment of axon-dendrite polarity and synaptic development. However, little information exists regarding the localized activity and regulation of these kinases in developing neurons. In this study, using a fluorescence resonance energy tran ...[more]