Ontology highlight
ABSTRACT:
SUBMITTER: Zhu XY
PROVIDER: S-EPMC4446869 | biostudies-other | 2015 Jun
REPOSITORIES: biostudies-other
Zhu Xiang-Yang XY Ebrahimi Behzad B Eirin Alfonso A Woollard John R JR Tang Hui H Jordan Kyra L KL Ofori Michael M Saad Ahmed A Herrmann Sandra M S SM Dietz Allan B AB Textor Stephen C SC Lerman Amir A Lerman Lilach O LO
Journal of the American Society of Nephrology : JASN 20140930 6
MicroRNA-26a (miR-26a) is a post-transcriptional regulator that inhibits cellular differentiation and apoptosis. Renal vascular disease (RVD) induces ischemic injury characterized by tubular cell apoptosis and interstitial fibrosis. We hypothesized that miR-26a levels are reduced in the poststenotic kidney and that kidney repair achieved by adipose tissue-derived mesenchymal stem cells (ad-MSCs) is associated with restored miR-26a levels. Renal function and renal miR-26a levels were assessed in ...[more]