Ontology highlight
ABSTRACT:
SUBMITTER: Tsoi SK
PROVIDER: S-EPMC4458553 | biostudies-other | 2015
REPOSITORIES: biostudies-other
Tsoi Shu Ki SK Smeesters Pierre R PR Frost Hannah R C HR Licciardi Paul P Steer Andrew C AC
Journal of immunology research 20150525
Group A streptococcus (GAS) is known to cause a broad spectrum of illness, from pharyngitis and impetigo, to autoimmune sequelae such as rheumatic heart disease, and invasive diseases. It is a significant cause of infectious disease morbidity and mortality worldwide, but no efficacious vaccine is currently available. Progress in GAS vaccine development has been hindered by a number of obstacles, including a lack of standardization in immunoassays and the need to define human correlates of protec ...[more]