Ontology highlight
ABSTRACT:
SUBMITTER: Mao S
PROVIDER: S-EPMC4491052 | biostudies-other | 2015 Jul
REPOSITORIES: biostudies-other
Mao Susu S Sun Qi Q Xiao Hui H Zhang Chenyu C Li Liang L
Protein & cell 20150620 7
MicroRNAs (miRNAs) are a class of noncoding RNAs that regulates target gene expression at posttranscriptional level, leading to further biological functions. We have demonstrated that microvesicles (MVs) can deliver miRNAs into target cells as a novel way of intercellular communication. It is reported that in central nervous system, glial cells release MVs, which modulate neuronal function in normal condition. To elucidate the potential role of glial MVs in disease, we evaluated the effects of s ...[more]