Pharmacometrics Markup Language (PharmML): Opening New Perspectives for Model Exchange in Drug Development.
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ABSTRACT:
SUBMITTER: Swat MJ
PROVIDER: S-EPMC4505825 | biostudies-other | 2015 Jun
REPOSITORIES: biostudies-other
Publications
Pharmacometrics Markup Language (PharmML): Opening New Perspectives for Model Exchange in Drug Development.
Swat M J MJ Moodie S S Wimalaratne S M SM Kristensen N R NR Lavielle M M Mari A A Magni P P Smith M K MK Bizzotto R R Pasotti L L Mezzalana E E Comets E E Sarr C C Terranova N N Blaudez E E Chan P P Chard J J Chatel K K Chenel M M Edwards D D Franklin C C Giorgino T T Glont M M Girard P P Grenon P P Harling K K Hooker A C AC Kaye R R Keizer R R Kloft C C Kok J N JN Kokash N N Laibe C C Laveille C C Lestini G G Mentré F F Munafo A A Nordgren R R Nyberg H B HB Parra-Guillen Z P ZP Plan E E Ribba B B Smith G G Trocóniz I F IF Yvon F F Milligan P A PA Harnisch L L Karlsson M M Hermjakob H H Le Novère N N
CPT: pharmacometrics & systems pharmacology 20150615 6
The lack of a common exchange format for mathematical models in pharmacometrics has been a long-standing problem. Such a format has the potential to increase productivity and analysis quality, simplify the handling of complex workflows, ensure reproducibility of research, and facilitate the reuse of existing model resources. Pharmacometrics Markup Language (PharmML), currently under development by the Drug Disease Model Resources (DDMoRe) consortium, is intended to become an exchange standard in ...[more]
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