Ontology highlight
ABSTRACT:
SUBMITTER: Li B
PROVIDER: S-EPMC4508837 | biostudies-other | 2015
REPOSITORIES: biostudies-other
Scientific reports 20150721
The aim of this meta-analysis is to examine the effects of dexmedetomidine on serum inflammatory markers when administered perioperatively. We searched multiple electronic databases for relevant research papers, and carried out meta-analyses of weighted mean differences and interpreted in the light of statistical heterogeneity (I(2)). Fifteen RCTs recruiting 641 patients were included. Dexmedetomidine treatment significantly decreased interleukin-6 (IL-6), IL-8 and tumor necrosis factor-alpha (T ...[more]