Ontology highlight
ABSTRACT:
SUBMITTER: Arasada R
PROVIDER: S-EPMC4510844 | biostudies-other | 2015 Jul
REPOSITORIES: biostudies-other
Arasada Rajesh R Pollard Thomas D TD
Journal of cell science 20150514 13
F-BAR proteins are known to participate in cytokinesis, but their mechanisms are not well understood. Here we investigated Rga7p, an Schizosaccharomyces pombe F-BAR protein with a RhoGAP domain. Localization of Rga7p to the cytokinetic cleavage furrow depends on its F-BAR domain, actin filaments, the formins Cdc12p and For3p, and the presence of a contractile ring. Rga7p is not required for the constriction of the contractile ring but does participate in the transport of a β-glucan synthetase (B ...[more]