Ontology highlight
ABSTRACT:
SUBMITTER: McLaughlin I
PROVIDER: S-EPMC4542051 | biostudies-other | 2015
REPOSITORIES: biostudies-other
McLaughlin Ian I Dani John A JA De Biasi Mariella M
Current topics in behavioral neurosciences 20150101
An aversive abstinence syndrome manifests 4-24 h following cessation of chronic use of nicotine-containing products. Symptoms peak on approximately the 3rd day and taper off over the course of the following 3-4 weeks. While the severity of withdrawal symptoms is largely determined by how nicotine is consumed, certain short nucleotide polymorphisms (SNPs) have been shown to predispose individuals to consume larger amounts of nicotine more frequently--as well as to more severe symptoms of withdraw ...[more]