Ontology highlight
ABSTRACT:
SUBMITTER: Bienkowski M
PROVIDER: S-EPMC4542181 | biostudies-other | 2015 Sep-Oct
REPOSITORIES: biostudies-other
Bienkowski Michal M Berghoff Anna S AS Marosi Christine C Wöhrer Adelheid A Heinzl Harald H Hainfellner Johannes A JA Preusser Matthias M
Clinical neuropathology 20150901 5
O6-methylguanine-methyltransferase (MGMT) promoter methylation status has prognostic and, in the subpopulation of elderly patients, predictive value in newly diagnosed glioblastoma. Therefore, knowledge of the MGMT promoter methylation status is important for clinical decision-making. So far, MGMT testing has been limited by the lack of a robust test with sufficiently high analytical performance. Recently, one of several available pyrosequencing protocols has been shown to be an accurate and rob ...[more]