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Evaluation of the Effectiveness of a Psychoeducational Intervention in Treatment-Naive Patients with Antidepressant Medication in Primary Care: A Randomized Controlled Trial.


ABSTRACT: There is evidence supporting the effectiveness of psychoeducation (PE) in patients with symptoms of depression in primary care (PC), but very few studies have assessed this intervention in antidepressant-naïve patients. The aim of this study is to assess the effectiveness of a PE program in these patients, since the use of antidepressant (AD) medication may interfere with the effects of the intervention.106 participants were included, 50 from the PE program (12 weekly 1.5-hour sessions) and 56 from the control group (CG) that received the usual care. Patients were assessed at baseline and at 3, 6, and 9 months. The main outcome measures were the Beck Depression Inventory (BDI) and remission based on the BDI. The analysis was carried out on an intention-to-treat basis.The PE program group showed remission of symptoms of 40% (P = 0.001) posttreatment and 42% (P = 0.012) at 6 months. The analysis only showed significant differences in the BDI score posttreatment (P = 0.008; effect size Cohen's d' = 0.55).The PE intervention is an effective treatment in the depressive population not treated with AD medication. Before taking an AD, psychoeducational intervention should be considered.

SUBMITTER: Casanas R 

PROVIDER: S-EPMC4562075 | biostudies-other | 2015

REPOSITORIES: biostudies-other

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Evaluation of the Effectiveness of a Psychoeducational Intervention in Treatment-Naïve Patients with Antidepressant Medication in Primary Care: A Randomized Controlled Trial.

Casañas R R   Catalán R R   Penadés R R   Real J J   Valero S S   Muñoz Ma M   Lalucat-Jo Ll L   Casas M M  

TheScientificWorldJournal 20150825


<h4>Background</h4>There is evidence supporting the effectiveness of psychoeducation (PE) in patients with symptoms of depression in primary care (PC), but very few studies have assessed this intervention in antidepressant-naïve patients. The aim of this study is to assess the effectiveness of a PE program in these patients, since the use of antidepressant (AD) medication may interfere with the effects of the intervention.<h4>Methods</h4>106 participants were included, 50 from the PE program (12  ...[more]

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