Ontology highlight
ABSTRACT:
SUBMITTER: Gondo Y
PROVIDER: S-EPMC45647 | biostudies-other | 1993 Jan
REPOSITORIES: biostudies-other
Gondo Y Y Gardner J M JM Nakatsu Y Y Durham-Pierre D D Deveau S A SA Kuper C C Brilliant M H MH
Proceedings of the National Academy of Sciences of the United States of America 19930101 1
The mouse pink-eyed unstable (p(un)) mutation, affecting coat color, exhibits one of the highest reported reversion frequencies of any mammalian mutation and is associated with a duplication of genomic DNA at the p locus. In this study, genomic clones containing the boundaries of the p(un) duplication were isolated and characterized. The structure of these sequences and their wild-type and revertant counterparts were analyzed by restriction mapping, PCR product analysis, DNA sequence analysis, a ...[more]