Ontology highlight
ABSTRACT:
SUBMITTER: Gan-Or Z
PROVIDER: S-EPMC4574811 | biostudies-other | 2015 Sep
REPOSITORIES: biostudies-other
Annals of clinical and translational neurology 20150731 9
Rapid eye movement sleep behavior disorder and GBA mutations are both associated with Parkinson's disease. The GBA gene was sequenced in idiopathic rapid eye movement sleep behavior disorder patients (n = 265), and compared to controls (n = 2240). Rapid eye movement sleep behavior disorder questionnaire was performed in an independent Parkinson's disease cohort (n = 120). GBA mutations carriers had an OR of 6.24 (10.2% in patients vs. 1.8% in controls, P < 0.0001) for rapid eye movement sleep be ...[more]