Ontology highlight
ABSTRACT:
SUBMITTER: Stuart SA
PROVIDER: S-EPMC4585806 | biostudies-other | 2015 Sep
REPOSITORIES: biostudies-other
Stuart Sarah A SA Robinson Emma S J ES
Scientific reports 20150923
Restraint in animals is known to cause stress but is used during almost all scientific procedures in rodents, representing a major welfare and scientific issue. Administration of substances, a key part of most scientific procedures, almost always involves physical restraint of the animal. In this study, we developed a method to inject substances to rats using a non-restrained technique. We then compared the physiological, behavioral and emotional impacts of restrained versus non-restrained injec ...[more]