Dataset Information

Electrochemical Bioelectronic Device Consisting of Metalloprotein for Analog Decision Making.

ABSTRACT: We demonstrate an analog type logical device that combines metalloprotein and organic/inorganic materials and can make an interactive analog decision. Myoglobin is used as a functional biomolecule to generate electrochemical signals, and its original redox signal is controlled with various mercapto-acids by the distance effect between myoglobin and a metal surface in the process of electron transfer. Controlled signals are modulated with the introduction of inorganic materials including nanoparticles and metal ions. By forming a hybrid structure with various constituents of organic/inorganic materials, several functions for signal manipulation were achieved, including enhancement, suppression, and shift. Based on the manipulated signals of biomolecules, a novel logical system for interactive decision-making processes is proposed by selectively combining different signals. Through the arrangement of various output signals, we can define interactive logical results regulated by an inherent tendency (by metalloprotein), personal experience (by organic spacer sets), and environments (by inorganic materials). As a practical application, a group decision process is presented using the proposed logical device. The proposed flexible logic process could facilitate the realization of an artificial intelligence system by mimicking the sophisticated human logic process.

SUBMITTER: Chung YH

PROVIDER: S-EPMC4585857 | biostudies-other | 2015

REPOSITORIES: biostudies-other

ACCESS DATA

Publications

Electrochemical Bioelectronic Device Consisting of Metalloprotein for Analog Decision Making.

Chung Yong-Ho YH Lee Taek T Yoo Si-Youl SY Min Junhong J Choi Jeong-Woo JW

Scientific reports 20150924

We demonstrate an analog type logical device that combines metalloprotein and organic/inorganic materials and can make an interactive analog decision. Myoglobin is used as a functional biomolecule to generate electrochemical signals, and its original redox signal is controlled with various mercapto-acids by the distance effect between myoglobin and a metal surface in the process of electron transfer. Controlled signals are modulated with the introduction of inorganic materials including nanopart ...[more]

PMID: 26400018

Similar Datasets

Project description:BACKGROUND:This study explores the role of pleasure in decision making. RESULTS:In Experiment 1, 12 subjects were presented with a questionnaire containing 46 items taken from the literature. Twenty-three items described a situation where a decision should be made and ended with a suggested solution. The other items served as filler items. The subjects were requested not to make a decision but to rate the pleasure or displeasure they experienced when reading the situation described in the item. The subjects' ratings were then compared to the decisions on the same situations made by the other subjects of the studies published by other workers. The ratings of pleasure/displeasure given by our subjects correlated significantly with the choices published by other authors. This result satisfies a necessary condition for pleasure to be the key of the decision making process in theoretical situations. In Experiment 2, a new group of 12 subjects rated their experience of pleasure/displeasure when reading various versions of 50 situations taken from daily life where an ethical decision had to be made (Questionnaire I) including 200 items. This was followed by a multiple-choice test with the 50 situations (Questionnaire II) using the same 200 items and offering the various behaviors. Subjects tended to choose ethical and unethical responses corresponding to their highest pleasure rating within each problem. In all cases the subjects' behavior was higher than chance level, and thus, followed the trend to maximize pleasure. In Experiment 3, 12 subjects reading 50 mathematical short problems followed by correct and incorrect versions of the answer to the problem (Questionnaire III), including 200 items. This was followed by a multiple-choice mathematical test with the 50 problems (Questionnaire IV) using the same 200 items and offering the correct and incorrect answers. In questionnaire IV, subjects tended to choose correct as well as incorrect responses corresponding to their highest hedonic rating within each problem. In all cases the subjects' behavior was higher than chance level, and thus, followed the trend to maximize pleasure. CONCLUSIONS:The results of the three experiments support the hypothesis according to which decisions are made in the hedonic dimension of conscious experience.

Dataset Information

Electrochemical Bioelectronic Device Consisting of Metalloprotein for Analog Decision Making.

Publications

Electrochemical Bioelectronic Device Consisting of Metalloprotein for Analog Decision Making.

Similar Datasets

OmicsDI is part of the ELIXIR infrastructure

Tweets