Apoptosis, Necrosis, and Necroptosis in the Gut and Intestinal Homeostasis.
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ABSTRACT:
SUBMITTER: Negroni A
PROVIDER: S-EPMC4592906 | biostudies-other | 2015
REPOSITORIES: biostudies-other
Publications
Apoptosis, Necrosis, and Necroptosis in the Gut and Intestinal Homeostasis.
Negroni Anna A Cucchiara Salvatore S Stronati Laura L
Mediators of inflammation 20150921
Intestinal epithelial cells (IECs) form a physiochemical barrier that separates the intestinal lumen from the host's internal milieu and is critical for electrolyte passage, nutrient absorption, and interaction with commensal microbiota. Moreover, IECs are strongly involved in the intestinal mucosal inflammatory response as well as in mucosal innate and adaptive immune responses. Cell death in the intestinal barrier is finely controlled, since alterations may lead to severe disorders, including ...[more]
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