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Locoregional treatment for hepatocellular carcinoma: The best is yet to come.

ABSTRACT: Hepatocellular carcinoma (HCC) is the sixth-most common type of cancer worldwide. The only definitive treatment modalities capable of achieving a cure are hepatic resection and hepatic transplantation. However, most patients are not candidates for these therapies. Overall, treatment options are driven by the stage of HCC. Early-stage disease is treated with ablative therapies, with radiofrequency ablation the ablative therapy of choice. Microwave ablation and irreversible electroporation are the other upcoming alternatives. Intermediate-stage disease is managed with transarterial chemoembolization (TACE), while advanced-stage disease is managed by sorafenib, with TACE and radioembolization as other alternatives.

SUBMITTER: Kalra N

PROVIDER: S-EPMC4620111 | biostudies-other | 2015 Oct

REPOSITORIES: biostudies-other

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Locoregional treatment for hepatocellular carcinoma: The best is yet to come.

Kalra Naveen N Gupta Pankaj P Chawla Yogesh Y Khandelwal Niranjan N

World journal of radiology 20151001 10

Hepatocellular carcinoma (HCC) is the sixth-most common type of cancer worldwide. The only definitive treatment modalities capable of achieving a cure are hepatic resection and hepatic transplantation. However, most patients are not candidates for these therapies. Overall, treatment options are driven by the stage of HCC. Early-stage disease is treated with ablative therapies, with radiofrequency ablation the ablative therapy of choice. Microwave ablation and irreversible electroporation are the ...[more]

PMID: 26516427

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