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Serum Osteocalcin Is Associated with Inflammatory Factors in Metabolic Syndrome: A Population-Based Study in Chinese Males.


ABSTRACT: Osteocalcin (OCN) was potentially associated with inflammatory factors, so we explored the metabolic role in this association in general population. Our findings suggest that OCN was positively associated with IgG while inversely associated with C3, both of which were probably mediated by obesity. Moreover, serum OCN was inversely associated with hsCRP in men with impaired fasting glucose, hyperglycemia, or metabolic syndrome, while its association with IgE was significantly observed in men with a normal metabolic profile.

SUBMITTER: Liao M 

PROVIDER: S-EPMC4633571 | biostudies-other | 2015

REPOSITORIES: biostudies-other

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Serum Osteocalcin Is Associated with Inflammatory Factors in Metabolic Syndrome: A Population-Based Study in Chinese Males.

Liao Ming M   Huang Lirong L   Mao Yan Y   Jiang Yonghua Y   Yao Ziting Z   Lin Xinggu X   Lu Zheng Z   Wu Chunlei C   Qin Xue X   Zhang Haiying H   Mo Zengnan Z  

Mediators of inflammation 20151022


Osteocalcin (OCN) was potentially associated with inflammatory factors, so we explored the metabolic role in this association in general population. Our findings suggest that OCN was positively associated with IgG while inversely associated with C3, both of which were probably mediated by obesity. Moreover, serum OCN was inversely associated with hsCRP in men with impaired fasting glucose, hyperglycemia, or metabolic syndrome, while its association with IgE was significantly observed in men with  ...[more]

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