FluBlok, a recombinant hemagglutinin influenza vaccine.
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ABSTRACT:
SUBMITTER: Cox MM
PROVIDER: S-EPMC4634115 | biostudies-other | 2008 Nov
REPOSITORIES: biostudies-other
Publications
FluBlok, a recombinant hemagglutinin influenza vaccine.
Cox Manon M J MM Patriarca Peter A PA Treanor John J
Influenza and other respiratory viruses 20081101 6
FluBlok, a recombinant trivalent hemagglutinin (HA) vaccine produced in insect cell culture using the baculovirus expression system, provides an attractive alternative to the current egg-based trivalent inactivated influenza vaccine (TIV) manufacturing process. FluBlok contains three times more HA than TIV and does not contain egg-protein or preservatives. This review discusses the four main clinical studies that were used to support licensure of FluBlok under the 'Accelerated Approval' mechanis ...[more]
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