Ontology highlight
ABSTRACT:
SUBMITTER: Ji J
PROVIDER: S-EPMC4637860 | biostudies-other | 2015 Nov
REPOSITORIES: biostudies-other
Ji Juan J Qin Yufeng Y Ren Jing J Lu Chuncheng C Wang Rong R Dai Xiuliang X Zhou Ran R Huang Zhenyao Z Xu Miaofei M Chen Minjian M Wu Wei W Song Ling L Shen Hongbing H Hu Zhibin Z Miao Dengshun D Xia Yankai Y Wang Xinru X
Scientific reports 20151109
Mitochondria-related microRNAs (miRNAs) have recently emerged as key regulators of cell metabolism and can modulate mitochondrial fusion and division. In order to investigate the roles of mitochondria-related miRNAs played in obesity, we conducted comprehensive molecular analysis in vitro and in vivo. Based on high-fat-diet (HFD) induced obese mice, we found that hepatic mitochondrial function was markedly altered. Subsequently, we evaluated the expression levels of selected mitochondria-related ...[more]