Ontology highlight
ABSTRACT:
SUBMITTER: Cui J
PROVIDER: S-EPMC4637884 | biostudies-other | 2015
REPOSITORIES: biostudies-other
Cui Jie J Tachedjian Gilda G Wang Lin-Fa LF
Scientific reports 20151109
Endogenous retroviruses (ERVs) represent past retroviral infections and accordingly can provide an ideal framework to infer virus-host interaction over their evolutionary history. In this study, we target high quality Pol sequences from 7,994 Class I and 8,119 Class II ERVs from 69 mammalian genomes and surprisingly find that retroviruses harbored by bats and rodents combined occupy the major phylogenetic diversity of both classes. By analyzing transmission patterns of 30 well-defined ERV clades ...[more]