Ontology highlight
ABSTRACT:
SUBMITTER: Homouz D
PROVIDER: S-EPMC4649851 | biostudies-other | 2015 Mar
REPOSITORIES: biostudies-other
Homouz Dirar D Chen Gang G Kudlicki Andrzej S AS
Scientific reports 20150313
We report and model a previously undescribed systematic error causing spurious excess correlations that depend on the distance between probes on Affymetrix® microarrays. The phenomenon affects pairs of features with large chip separations, up to over 100 probes apart. The effect may have a significant impact on analysis of correlations in large collections of expression data, where the systematic experimental errors are repeated in many data sets. Examples of such studies include analysis of fun ...[more]