Unknown

Dataset Information

0

Ultrasound-guided percutaneous microwave ablation for adenomyosis: efficacy of treatment and effect on ovarian function.


ABSTRACT: A total of 142 premenopausal women with symptomatic adenomyosis underwent ultrasound (US)-guided percutaneous microwave ablation (PMWA) at the Chinese PLA General Hospital. This study aimed to evaluate changes in serum pituitary, gonadal hormone and cancer antigen 125 (CA125) levels after US-guided PMWA. Therefore, estradiol (E2), follicle-stimulating hormone (FSH), prolactin (PRL) and CA125 levels were evaluated before ablation and at 3, 6, 9 and 12 months after ablation. No significant differences were observed in the E2 and FSH levels pre-ablation and during follow-up (E2: p=0.933, p=0.987, p=0.106, p=0.936; FSH: p=0.552, p=0.295, p=0.414, p=0.760). The mean absolute values of serum CA125 and PRL were significantly decreased at 3, 6, 9 and 12 months after ablation (CA125: p<0.001, p<0.001, p<0.001, p=0.003; PRL: p<0.001, p<0.001, p<0.001, p<0.001). A significant correlation between changes in CA125 levels and uterine volume was found (p<0.001). No evidence of a decline in ovarian function was observed after US-guided PMWA.

SUBMITTER: Yang Y 

PROVIDER: S-EPMC4650326 | biostudies-other | 2015

REPOSITORIES: biostudies-other

Similar Datasets

| S-EPMC5733153 | biostudies-literature
| S-EPMC6614164 | biostudies-literature
| S-EPMC9987667 | biostudies-literature
| S-EPMC9096293 | biostudies-literature
| S-EPMC10650828 | biostudies-literature
| S-EPMC8154784 | biostudies-literature
| S-EPMC9950924 | biostudies-literature
| S-EPMC5573330 | biostudies-literature
| S-EPMC8743408 | biostudies-literature
| S-EPMC7298123 | biostudies-literature