Ontology highlight
ABSTRACT:
SUBMITTER: Huang X
PROVIDER: S-EPMC4655588 | biostudies-other | 2015 Apr
REPOSITORIES: biostudies-other
Journal of labelled compounds & radiopharmaceuticals 20150218 4
To synthesize (18) F-labeled positron emission tomography (PET) ligands, reliable labeling techniques inserting (18) F into a target molecule are necessary. The (18) F-fluorobenzene moiety has been widely utilized in the synthesis of (18) F-labeled compounds. The present study utilized [(18) F]-labeled aniline as intermediate in [(18) F]-radiolabeling chemistry for the facile radiosynthesis of 4-amino-N-(3-chloro-4-fluorophenyl)-N'-hydroxy-1,2,5-oxadiazole-3-carboximidamide ([(18) F]IDO5L) as in ...[more]