Ontology highlight
ABSTRACT:
SUBMITTER: Collins DJ
PROVIDER: S-EPMC4659840 | biostudies-other | 2015
REPOSITORIES: biostudies-other
Collins David J DJ Morahan Belinda B Garcia-Bustos Jose J Doerig Christian C Plebanski Magdalena M Neild Adrian A
Nature communications 20151102
In single-cell analysis, cellular activity and parameters are assayed on an individual, rather than population-average basis. Essential to observing the activity of these cells over time is the ability to trap, pattern and retain them, for which previous single-cell-patterning work has principally made use of mechanical methods. While successful as a long-term cell-patterning strategy, these devices remain essentially single use. Here we introduce a new method for the patterning of multiple spat ...[more]