Ontology highlight
ABSTRACT:
SUBMITTER: Hirakawa Y
PROVIDER: S-EPMC4672317 | biostudies-other | 2015 Dec
REPOSITORIES: biostudies-other
Scientific reports 20151208
Hypoxia appears to have an important role in pathological conditions in many organs such as kidney; however, a method to quantify intracellular oxygen tension in vivo has not been well established. In this study, we established an optical method to quantify oxygen tension in mice kidneys using a cationic lipophilic phosphorescence probe, BTPDM1, which has an intracellular oxygen concentration-sensitive phosphorescence lifetime. Since this probe is distributed inside the tubular cells of the mice ...[more]