Ontology highlight
ABSTRACT:
SUBMITTER: Im JY
PROVIDER: S-EPMC4675896 | biostudies-other | 2015 Dec
REPOSITORIES: biostudies-other
Im Joo-Young JY Lee Kang-Woo KW Won Kyoung-Jae KJ Kim Bo-Kyung BK Ban Hyun Seung HS Yoon Sung-Hoon SH Lee Young-Ju YJ Kim Young-Joo YJ Song Kyung-Bin KB Won Misun M
Data in brief 20151117
DNA damage induced apoptosis suppressor (DDIAS), or human Noxin (hNoxin), is strongly expressed in lung cancers. DDIAS knockdown induced apoptosis in non-small cell lung carcinoma A549 cells in response to DNA damage, indicating DDIAS as a potential therapeutic target in lung cancer. To understand the transcriptional regulation of DDIAS, we determined the transcription start site, promoter region, and transcription factor. We found that DDIAS transcription begins at nucleotide 212 upstream of th ...[more]