Ontology highlight
ABSTRACT:
SUBMITTER: Taleahmad S
PROVIDER: S-EPMC4680864 | biostudies-other | 2015 Dec
REPOSITORIES: biostudies-other
Taleahmad Sara S Mirzaei Mehdi M Parker Lindsay M LM Hassani Seyedeh-Nafiseh SN Mollamohammadi Sepideh S Sharifi-Zarchi Ali A Haynes Paul A PA Baharvand Hossein H Salekdeh Ghasem Hosseini GH
Scientific reports 20151216
The differentiation potential of pluripotent embryonic stem cells (ESCs) can be manipulated via serum and medium conditions for direct cellular development or to maintain a naïve ground state. The self-renewal state of ESCs can thus be induced by adding inhibitors of mitogen activated protein kinase (MAPK) and glycogen synthase kinase-3 (Gsk3), known as 2 inhibitors (2i) treatment. We have used a shotgun proteomics approach to investigate differences in protein expressions between 2i- and serum- ...[more]