Ontology highlight
ABSTRACT:
SUBMITTER: Lin CH
PROVIDER: S-EPMC4680865 | biostudies-other | 2015 Dec
REPOSITORIES: biostudies-other
Lin Ching-Hung CH Chen I-Chiun IC Huang Chiun-Sheng CS Hu Fu-Chang FC Kuo Wen-Hung WH Kuo Kuan-Ting KT Wang Chung-Chieh CC Wu Pei-Fang PF Chang Dwan-Ying DY Wang Ming-Yang MY Chang Chin-Hao CH Chen Wei-Wu WW Lu Yen-Shen YS Cheng Ann-Lii AL
Scientific reports 20151216
IHC4 and PAM50 assays have been shown to provide additional prognostic information for patients with early breast cancer. We evaluated whether incorporating TP53 mutation analysis can further enhance their prognostic accuracy. We examined TP53 mutation and the IHC4 score in tumors of 605 patients diagnosed with stage I-III breast cancer at National Taiwan University Hospital (the NTUH cohort). We obtained information regarding TP53 mutation and PAM50 subtypes in 699 tumors from the Molecular Tax ...[more]