Ontology highlight
ABSTRACT:
SUBMITTER: Yuan F
PROVIDER: S-EPMC4680876 | biostudies-other | 2015 Dec
REPOSITORIES: biostudies-other
Yuan Fang F Fang Kai-Heng KH Cao Shi-Ying SY Qu Zhuang-Yin ZY Li Qi Q Krencik Robert R Xu Min M Bhattacharyya Anita A Su Yu-Wen YW Zhu Dong-Ya DY Liu Yan Y
Scientific reports 20151216
Human pluripotent stem cells (hPSCs) have potential to differentiate to unlimited number of neural cells, which provide powerful tools for neural regeneration. To date, most reported protocols were established with an animal feeder system. However, cells derived on this system are inappropriate for the translation to clinical applications because of the introduction of xenogenetic factors. In this study, we provided an optimized paradigm to generate region-specific forebrain neurons from hPSCs u ...[more]