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Diterpenoids from the Roots of Salvia yunnanensis.

ABSTRACT: Two new diterpenoids, salyunnanins I and J (1 and 2), together with ten analogues, were isolated from the roots of Salvia yunnanensis. The structures of the new isolates, possessing different neo-clerodane and seco-abietane diterpenoid skeletons respectively, were elucidated on the basis of comprehensive spectroscopic data. All of the compounds were tested for the inhibitory activities against six human tumor lines in vitro, and several ones showed moderate cytotoxic activities.

SUBMITTER: Xia F

PROVIDER: S-EPMC4681706 | biostudies-other | 2015 Dec

REPOSITORIES: biostudies-other

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Diterpenoids from the Roots of Salvia yunnanensis.

Xia Fan F Wu Chun-Yan CY Yang Xing-Wei XW Li Xian X Xu Gang G

Natural products and bioprospecting 20151214 6

Two new diterpenoids, salyunnanins I and J (1 and 2), together with ten analogues, were isolated from the roots of Salvia yunnanensis. The structures of the new isolates, possessing different neo-clerodane and seco-abietane diterpenoid skeletons respectively, were elucidated on the basis of comprehensive spectroscopic data. All of the compounds were tested for the inhibitory activities against six human tumor lines in vitro, and several ones showed moderate cytotoxic activities. ...[more]

PMID: 26667937

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