Ontology highlight
ABSTRACT:
SUBMITTER: Kim M
PROVIDER: S-EPMC4682086 | biostudies-other | 2015 Dec
REPOSITORIES: biostudies-other
Kim Minji M Kim Minji M Goto Tsuyoshi T Yu Rina R Uchida Kunitoshi K Tominaga Makoto M Kano Yuriko Y Takahashi Nobuyuki N Kawada Teruo T
Scientific reports 20151217
Brown adipose tissue (BAT) plays a central role in regulating energy homeostasis, and may provide novel strategies for the treatment of human obesity. BAT-mediated thermogenesis is regulated by mitochondrial uncoupling protein 1 (UCP1) in classical brown and ectopic beige adipocytes, and is controlled by sympathetic nervous system (SNS). Previous work indicated that fish oil intake reduces fat accumulation and induces UCP1 expression in BAT; however, the detailed mechanism of this effect remains ...[more]