Molecular Genetic Testing in Pain and Addiction: Facts, Fiction and Clinical Utility.
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ABSTRACT:
SUBMITTER: Blum K
PROVIDER: S-EPMC4720149 | biostudies-other | 2015 Jul
REPOSITORIES: biostudies-other
Publications
Molecular Genetic Testing in Pain and Addiction: Facts, Fiction and Clinical Utility.
Blum Kenneth K Hauser Mary M Fratantonio James J Badgaiyan Rajendra D RD
Addiction genetics 20150701 1
The Brain Reward Cascade (BRC) is an interaction of neurotransmitters and their respective genes to control the amount of dopamine released within the brain. Any variations within this pathway, whether genetic or environmental (epigenetic), may result in addictive behaviors as well as altered pain tolerance. While there are many studies claiming a genetic association with addiction and other behavioral infractions, defined as Reward Deficiency Syndrome (RDS), not all are scientifically accurate ...[more]
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