Ontology highlight
ABSTRACT:
SUBMITTER: Wang M
PROVIDER: S-EPMC4728021 | biostudies-other | 2016 Feb
REPOSITORIES: biostudies-other
Wang Molin M Spiegelman Donna D Kuchiba Aya A Lochhead Paul P Kim Sehee S Chan Andrew T AT Poole Elizabeth M EM Tamimi Rulla R Tworoger Shelley S SS Giovannucci Edward E Rosner Bernard B Ogino Shuji S
Statistics in medicine 20151201 5
A fundamental goal of epidemiologic research is to investigate the relationship between exposures and disease risk. Cases of the disease are often considered a single outcome and assumed to share a common etiology. However, evidence indicates that many human diseases arise and evolve through a range of heterogeneous molecular pathologic processes, influenced by diverse exposures. Pathogenic heterogeneity has been considered in various neoplasms such as colorectal, lung, prostate, and breast canc ...[more]