Unknown

Dataset Information

0

Proteomic Profiling of Serum-Derived Exosomes from Ethnically Diverse Prostate Cancer Patients.


ABSTRACT: Prostate cancer (PCa) remains the most frequently diagnosed male malignancy in Western countries and the second most common cause of male cancer death in the United States. The relatively elevated PCa incidence and mortality among African American men makes this cancer type a challenging health disparity disease. To increase the chance for successful trea tment, earlier detection and prediction of tumor aggress iveness will be important and need to be resolved. This study demonstrates that small membrane-bound vesicles shed from the tumor called exosomes contain ethnically and tumor-specific biomarkers, and could be exploited for their diagnostic and therapeutic potential.

SUBMITTER: Turay D 

PROVIDER: S-EPMC4732892 | biostudies-other | 2016

REPOSITORIES: biostudies-other

altmetric image

Publications

Proteomic Profiling of Serum-Derived Exosomes from Ethnically Diverse Prostate Cancer Patients.

Turay David D   Khan Salma S   Diaz Osterman Carlos J CJ   Curtis Matthew P MP   Khaira Balreet B   Neidigh Jonathan W JW   Mirshahidi Saied S   Casiano Carlos A CA   Wall Nathan R NR  

Cancer investigation 20151104 1


Prostate cancer (PCa) remains the most frequently diagnosed male malignancy in Western countries and the second most common cause of male cancer death in the United States. The relatively elevated PCa incidence and mortality among African American men makes this cancer type a challenging health disparity disease. To increase the chance for successful trea tment, earlier detection and prediction of tumor aggress iveness will be important and need to be resolved. This study demonstrates that small  ...[more]

Similar Datasets

| S-EPMC7367030 | biostudies-literature
| S-EPMC6390805 | biostudies-other
| S-EPMC8215487 | biostudies-literature
| S-EPMC3876995 | biostudies-literature
| S-EPMC10576571 | biostudies-literature
| S-EPMC7442638 | biostudies-literature
| S-EPMC7352325 | biostudies-literature
| S-EPMC5462613 | biostudies-literature
| 2125831 | ecrin-mdr-crc
| S-EPMC4673300 | biostudies-literature