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Ammonium catalyzed cyclitive additions: evidence for a cation-? interaction with alkynes.

ABSTRACT: The addition of carbamate nitrogen to a non-conjugated carbon-carbon triple bond is catalyzed by an ammonium salt leading to a cyclic product. Studies in homogeneous systems suggest that the ammonium agent facilitates nitrogen-carbon bond formation through a cation-? interaction with the alkyne unit that, for the first time, is directly observed by Raman spectroscopy.

SUBMITTER: Nagy E

PROVIDER: S-EPMC4732893 | biostudies-other | 2016 Feb

REPOSITORIES: biostudies-other

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Ammonium catalyzed cyclitive additions: evidence for a cation-π interaction with alkynes.

Nagy Edith E St Germain Elijah E Cosme Patrick P Maity Pradip P Terentis Andrew C AC Lepore Salvatore D SD

Chemical communications (Cambridge, England) 20160201 11

The addition of carbamate nitrogen to a non-conjugated carbon-carbon triple bond is catalyzed by an ammonium salt leading to a cyclic product. Studies in homogeneous systems suggest that the ammonium agent facilitates nitrogen-carbon bond formation through a cation-π interaction with the alkyne unit that, for the first time, is directly observed by Raman spectroscopy. ...[more]

PMID: 26728333

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