Cartilage homeoprotein 1, a homeoprotein selectively expressed in chondrocytes.
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ABSTRACT:
SUBMITTER: Zhao GQ
PROVIDER: S-EPMC47412 | biostudies-other | 1993 Sep
REPOSITORIES: biostudies-other
Publications
Cartilage homeoprotein 1, a homeoprotein selectively expressed in chondrocytes.
Zhao G Q GQ Zhou X X Eberspaecher H H Solursh M M de Crombrugghe B B
Proceedings of the National Academy of Sciences of the United States of America 19930901 18
We identified a rat cDNA that encodes cartilage homeoprotein 1 (Cart-1). The deduced amino acid sequence of Cart-1 contains a paired-type homeodomain. Northern blot hybridization and RNase protection assay revealed that Cart-1 RNA was present at high levels in a well-differentiated rat chondrosarcoma tumor and in a cell line derived from this tumor. Cart-1 RNA was detected in primary mouse and rat chondrocytes but not in various fibroblasts including mouse 10T1/2 cells, NIH 3T3 cells, BALB 3T3 c ...[more]
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