Ontology highlight
ABSTRACT:
SUBMITTER: Chen G
PROVIDER: S-EPMC4764827 | biostudies-other | 2016 Feb
REPOSITORIES: biostudies-other
Chen Guangxiang G Hu Xinyu X Li Lei L Huang Xiaoqi X Lui Su S Kuang Weihong W Ai Hua H Bi Feng F Gu Zhongwei Z Gong Qiyong Q
Scientific reports 20160224
White matter (WM) abnormalities have long been suspected in major depressive disorder (MDD). Tract-based spatial statistics (TBSS) studies have detected abnormalities in fractional anisotropy (FA) in MDD, but the available evidence has been inconsistent. We performed a quantitative meta-analysis of TBSS studies contrasting MDD patients with healthy control subjects (HCS). A total of 17 studies with 18 datasets that included 641 MDD patients and 581 HCS were identified. Anisotropic effect size-si ...[more]