Ontology highlight
ABSTRACT:
SUBMITTER: Hadjimichael C
PROVIDER: S-EPMC4788761 | biostudies-other | 2016 Mar
REPOSITORIES: biostudies-other
Hadjimichael Christiana C Nikolaou Christoforos C Papamatheakis Joseph J Kretsovali Androniki A
Stem cell reports 20160211 3
Over the past years, microRNAs (miRNAs) have emerged as crucial factors that regulate self-renewal and differentiation of embryonic stem cells (ESCs). Although much is known about their role in maintaining ESC pluripotency, the mechanisms by which they affect cell fate decisions remain poorly understood. By performing deep sequencing to profile miRNA expression in mouse ESCs (mESCs) and differentiated embryoid bodies (EBs), we identified four differentially expressed miRNAs. Among them, miR-191 ...[more]