Ontology highlight
ABSTRACT:
SUBMITTER: Russo AJ
PROVIDER: S-EPMC4791140 | biostudies-other | 2016 Mar
REPOSITORIES: biostudies-other
Russo Ashley J AJ Mathiowetz Alyssa J AJ Hong Steven S Welch Matthew D MD Campellone Kenneth G KG
Molecular biology of the cell 20160128 6
Small G-proteins are key regulatory molecules that activate the actin nucleation machinery to drive cytoskeletal rearrangements during plasma membrane remodeling. However, the ability of small G-proteins to interact with nucleation factors on internal membranes to control trafficking processes has not been well characterized. Here we investigated roles for members of the Rho, Arf, and Rab G-protein families in regulating WASP homologue associated with actin, membranes, and microtubules (WHAMM), ...[more]