Germ cell-specific expression of Cre recombinase using the VASA promoter in the pig.
Ontology highlight
ABSTRACT:
SUBMITTER: Song Y
PROVIDER: S-EPMC4794798 | biostudies-other | 2016 Jan
REPOSITORIES: biostudies-other
Publications
Germ cell-specific expression of Cre recombinase using the VASA promoter in the pig.
Song Yuning Y Lai Liangxue L Li Li L Huang Yongye Y Wang Anfeng A Tang Xiaochun X Pang Daxin D Li Zhanjun Z Ouyang Hongsheng H
FEBS open bio 20151229 1
The Cre-loxP system is a powerful tool for genetic analysis of distinct cell lineages and tissue-specific gene knockout in animal models. VASA is specifically expressed in reproductive tissues, and is known to play important roles in spermatogenesis and germ-cell growth. In this study, Cre recombinase transgenic pigs under the control of the VASA promoter were generated by somatic cell nuclear transfer. Germ cell-specific expression of Cre recombinase in VASA-Cre transgenic pigs was shown by wes ...[more]
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