Ontology highlight
ABSTRACT:
SUBMITTER: Liu YF
PROVIDER: S-EPMC4799822 | biostudies-other | 2016
REPOSITORIES: biostudies-other
Liu Ya-Fei YF Wen Cai-Yu-Zhu CY Chen Zhe Z Wang Yu Y Huang Ying Y Hu Yong-Hong YH Tu Sheng-Hao SH
Evidence-based complementary and alternative medicine : eCAM 20160306
Background. Wutou decoction (WTD) has been wildly applied in the treatment of rheumatoid arthritis and experimental arthritis in rats for many years. Epigenetic deregulation is associated with the aetiology of rheumatoid arthritis; however, the effects of WTD on epigenetic changes are unclear. This study is set to explore the effects of WTD on DNA methylation and histone modifications in rats with collagen-induced arthritis (CIA). Methods. The CIA model was established by the stimulation of coll ...[more]