Ontology highlight
ABSTRACT:
SUBMITTER: Sitters G
PROVIDER: S-EPMC4805865 | biostudies-other | 2016 Jan
REPOSITORIES: biostudies-other
Sitters Gerrit G Laurens Niels N de Rijk Emilie J EJ Kress Holger H Peterman Erwin J G EJ Wuite Gijs J L GJ
Biophysical journal 20160101 1
The ability to measure and manipulate single molecules has greatly advanced the field of biophysics. Yet, the addition of more single-molecule tools that enable one to measure in a parallel fashion is important to diversify the questions that can be addressed. Here we present optical pushing (OP), a single-molecule technique that is used to exert forces on many individual biomolecules tethered to microspheres using a single collimated laser beam. Forces ranging from a few femtoNewtons to several ...[more]